JNg Volume 34 Cover

Volume 34, 2020

Table of Contents

Volume 34, Issue 3-4, 2020

Nature's Gift to Neuroscience:

A Tribute to Sydney Brenner and John Sulston



Nature’s gift to neuroscience

Joy Alcedo, Yishi Jin, Douglas S. Portman, Veena Prahlad, David Raizen, Georgia Rapti, X.Z. Shawn Xu, Yun Zhang & Chun-Fang Wu


Section 1: The early years of C. elegans neurogenetics


My life with Sydney, 1961–1971

Antony O. W. Stretton

John Sulston (1942–2018): a personal perspective

Robert H. Waterston & Donald G. Moerman

A touching story

Martin Chalfie

But can they learn? My accidental discovery of learning and memory in C. elegans

Catharine H. Rankin

Of worms and men

John White


Section 2: Nervous system development

A perspective on C. elegans neurodevelopment: from early visionaries to a booming neuroscience research

Georgia Rapti

Neuronal specification in C. elegans: combining lineage inheritance with intercellular signaling

Antoine Barrière & Vincent Bertrand

Molecular mechanisms governing axonal transport: a C. elegans perspective

Amruta Vasudevan & Sandhya P. Koushika

C. elegans MAGU-2/Mpp5 homolog regulates epidermal phagocytosis and synapse density

Salvatore J. Cherra III, Alexandr Goncharov, Daniela Boassa, Mark Ellisman & Yishi Jin

Synaptic remodeling, lessons from C. elegans

Andrea Cuentas-Condori & David M. Miller, 3rd

What about the males? the C. elegans sexually dimorphic nervous system and a CRISPR-based tool to study males in a hermaphroditic species

Jonathon D. Walsh, Olivier Boivin & Maureen M. Barr

Cell-type-specific promoters for C. elegans glia

Wendy Fung, Leigh Wexler & Maxwell G. Heiman

Section 3: From inputs to outputs

C. elegans: a sensible model for sensory biology

Adam J. Iliff & X.Z. Shawn Xu

Temperature signaling underlying thermotaxis and cold tolerance in Caenorhabditis elegans

Asuka Takeishi, Natsune Takagaki & Atsushi Kuhara

Mechano-gated channels in C. elegans

Umar Al-Sheikh & Lijun Kang

What can a worm learn in a bacteria-rich habitat?

He Liu & Yun Zhang

C. elegans aversive olfactory learning generates diverse intergenerational effects

Ana Goncalves Pereira, Xicotencatl Gracida, Konstantinos Kagias & Yun Zhang

Section 4: Social and sexual behaviors

Social and sexual behaviors in C. elegans: the first fifty years

Douglas S. Portman

Small molecule signals mediate social behaviors in C. elegans

Caroline S. Muirhead & Jagan Srinivasan

Intraguild predation between Pristionchus pacificus and Caenorhabditis elegans: a complex interaction with the potential for aggressive behaviour

Kathleen T. Quach & Sreekanth H. Chalasani

Plasticity of pheromone-mediated avoidance behavior in C. elegans

YongJin Cheon, Hyeonjeong Hwang & Kyuhyung Kim

Section 5: Quiescence and sleep

Worms sleep: a perspective

David Raizen

Cellular damage, including wounding, drives C. elegans stress-induced sleep

Desiree L. Goetting, Richard Mansfield, Rony Soto & Cheryl Van Buskirk

Orcokinin neuropeptides regulate sleep in Caenorhabditis elegans

Madison Honer, Kristen Buscemi, Natalie Barrett, Niknaz Riazati, Gerald Orlando & Matthew D. Nelson

Discriminating between sleep and exercise-induced fatigue using computer vision and behavioral genetics

Kelsey N. Schuch, Lakshmi Narasimhan Govindarajan, Yuliang Guo, Saba N. Baskoylu, Sarah Kim, Benjamin Kimia, Thomas Serre & Anne C. Hart

The OptoGenBox – a device for long-term optogenetics in C. elegans

Inka Busack, Florian Jordan, Peleg Sapir & Henrik Bringmann

Section 6: Survival, aging and disease

Neuromodulators: an essential part of survival

Joy Alcedo & Veena Prahlad

Neuroendocrine control of lipid metabolism: lessons from C. elegans

Supriya Srinivasan

The discovery and consequences of the central role of the nervous system in the control of protein homeostasis

Veena Prahlad

Host-microbe interactions and the behavior of Caenorhabditis elegans

Dennis H. Kim & Steven W. Flavell

Neurogenetics of nictation, a dispersal strategy in nematodes

Heeseung Yang, Bo Yun Lee, Hyunsoo Yim & Junho Lee

Regulatory systems that mediate the effects of temperature on the lifespan of Caenorhabditis elegans

Byounghun Kim, Jongsun Lee, Younghun Kim & Seung-Jae V. Lee

The contribution of C. elegans neurogenetics to understanding neurodegenerative diseases

Joseph J. H. Liang, Issa A. McKinnon & Catharine H. Rankin

Section 7: Worm Photo and Art Gallery

A journey to ‘tame a small metazoan organism’, ‡ seen through the artistic eyes of C. elegans researchers

Eleni Gourgou, Alexandra R. Willis, Sebastian Giunti, Maria J. De Rosa, Amanda G. Charlesworth, Mirella Hernandez Lima, Elizabeth Glater, Sonja Soo, Bianca Pereira, Kübra Akbaş, Anushka Deb, Madhushree Kamak, Mark W. Moyle, Annika Traa, Aakanksha Singhvi, Surojit Sural & Eugene Jennifer Jin


Volume 34, Issue 2, 2020


Review Article

Understanding neurobehavioral genetics of zebrafish

Sergey V. Cheresiz, Andrey D. Volgin, Alexandra Kokorina Evsyukova, Alim A.O. Bashirzade, Konstantin A. Demin, Murilo S. de Abreu, Tamara G. Amstislavskaya & Allan V. Kalueff

Original Research Article

Oxytocin ameliorates bone cancer pain by suppressing toll-like receptor 4 and proinflammatory cytokines in rat spinal cord

Xiaping Mou, Ji Fang, An Yang & Gang Du


Volume 34, Issue 1, 2020

Future perspectives of neurogenetics- in honor of Troy D. Zars (1967-2018)


Future perspectives of neurogenetics – in honor of Troy D. Zars (1967–2018)

Bertram Gerber, Elizabeth G. King, David Schulz, Hiromu Tanimoto, Scott Waddell & Chun-Fang Wu

Biographical Sketch

A biographical sketch of Troy D. Zars (1967–2018)

Bertram Gerber, Elizabeth G. King & Divya Sitaraman


Troy D. Zars: a personal tribute to a scientist, colleague, and friend

David J. Schulz

Memory, anticipation, action – working with Troy D. Zars

Reinhard Wolf, Martin Heisenberg, Björn Brembs, Scott Waddell, Aditi Mishra, Abigail Kehrer& Angelynn Simenson

Review Articles

Finding a place and leaving a mark in memory formation

Divya Sitaraman & Holly LaFerriere

Learning to collaborate: bringing together behavior and quantitative genomics

Patricka A. Williams-Simon, Mathangi Ganesan & Elizabeth G. King

Cellular and circuit mechanisms of olfactory associative learning in Drosophila

Tamara Boto, Aaron Stahl & Seth M. Tomchik

Optogenetics: Illuminating neuronal circuits of memory formation

Nadine Ehmann & Dennis Pauls

Significance of DopEcR, a G-protein coupled dopamine/ecdysteroid receptor, in physiological and behavioral response to stressors

Emily Petruccelli, Arianna Lark, James A. Mrkvicka & Toshihiro Kitamoto

Original Research Articles

Importin-α2 mediates brain development, learning and memory consolidation in Drosophila

Christine N. Serway, Brian S. Dunkelberger, Denise Del Padre, Nicole W. C. Nolan, Stephanie Georges, Stephanie Freer, Andrew J. Andres & J. Steven de Belle

Sleep restores place learning to the adenylyl cyclase mutant rutabaga

Stephane Dissel, Ellen Morgan, Vincent Duong, Dorothy Chan, Bruno van Swinderen, Paul Shaw & Troy Zars

Interactions between amyloid precursor protein-like (APPL) and MAGUK scaffolding proteins contribute to appetitive long-term memory in Drosophila melanogaster

Bryon Silva, Christian Niehage, Marta Maglione, Bernard Hoflack, Stephan J. Sigrist, Thomas Wassmer, Alice Pavlowsky & Thomas Preat

The Unc13A isoform is important for phasic release and olfactory memory formation at mushroom body synapses

Jennifer Woitkuhn, Anatoli Ender, Christine B. Beuschel, Marta Maglione, Tanja Matkovic-Rachid, Sheng Huang, Martin Lehmann, Joerg R. P. Geiger & Stephan J. Sigrist

Dopaminergic neurons can influence heat-box place learning in Drosophila

Aditi Mishra, Patrick Cronley, Mathangi Ganesan, David J. Schulz & Troy Zars

Food restriction reconfigures naïve and learned choice behavior in Drosophila larvae

Benita Brünner, Juliane Saumweber, Merve Samur, Denise Weber, Isabell Schumann, Deepthi Mahishi, Astrid Rohwedder & Andreas S. Thum

Differential localization of voltage-gated potassium channels during Drosophila metamorphosis

Jan Werner, Jashar Arian, Ida Bernhardt, Stefanie Ryglewski & Carsten Duch


Toward nanoscale localization of memory engrams in Drosophila

Yoshinori Aso & Gerald M. Rubin

Towards a functional connectome in Drosophila

Katrin Vogt

Studying neural circuits of decision-making in Drosophila larva

Tihana Jovanic

Studying complex brain dynamics using Drosophila

Sophie Aimon & Ilona C. Grunwald Kadow

Experimental psychology meets behavioral ecology: what laboratory studies of learning polymorphisms mean for learning under natural conditions, and vice versa

Brian H. Smith & Chelsea N. Cook

Cataglyphis meets Drosophila

Rüdiger Wehner

Playing the genome card

Ari Berkowitz

Minimal selfhood

R. D. V. Glasgow